Tedavi almamış major depresyon hastalarında erken dönemde bilişsel işlevler
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Tarih
2019
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info:eu-repo/semantics/openAccess
Özet
Bu araştırmada yeni tanı almış Major Depresif
Bozukluk (MDB) hastalarında bilişsel bozulmanın erken
dönemdeki düzeyinin sağlıklı kontrol grubu ile
karşılaştırılarak belirlenmesi amaçlanmıştır. Depresyon
tanısı alan kişilerin bilişsel işlevlerinden özellikle dikkat,
psikomotor hız ve yürütücü işlevlerde gelişebilecek
bozukluk düzeyinin tespit edilmesinin tedavi
programlarının geliştirilmesine katkı sağlayacağı
düşünülmüştür. Yöntem: Araştırmaya Adana Dr. Ekrem
Tok Ruh Sağlığı ve Hastalıkları Hastanesi Psikiyatri
polikliniğine başvuran tedavi almamış MDB tanısı alan 60
hasta ile cinsiyet ve yaş bakımından benzer olan depresyon tanısı almamış 30 kişiden oluşan kontrol grubu dahil
edilmiştir. Daha önce psikiyatrik bir hastalık tanısı ile
tedavi görmüş olan, son 6 aylık süre içerisinde ilaç veya
psikoterapi öyküsü olan hastalar çalışma dışı bırakılmıştır.
Araştırmada, Beck Depresyon Ölçeği (BDÖ) ve İz Sürme
Testi (İST) ölçme araçları olarak kullanılmıştır. Bulgular:
Çalışmada tedavi almamış MDB hastalarında erken
dönemde bilişsel işlevlerde bozulmanın sağlıklı kontrol
grubuna göre anlamlı olarak daha fazla olduğu
belirlenmiştir. İST puanlarında hasta ve kontrol grubu
arasında anlamlı farklılık olduğu saptanmıştır (p<0,005).
Depresyonun klinik şiddeti ile bilişsel bozulma düzeyi
arasında pozitif ve doğrusal bir ilişki olduğu sonucu elde
edilmiştir (A+B Süre; r=0,52, p<0,01). Sonuç: Erken
dönemde MDB hastalarında bilişsel bozulma göz önünde
bulundurulmalı ve bilişsel bozulmayı hedef alan
tedavilere yer verilmelidi
In this study, we aimed to determine the early stage of cognitive impairment in newly diagnosed Major Depressive Disorder (MDD) patients by comparing them with the healthy control group. The cognitive functions of the people diagnosed with depression, especially attention, psychomotor speed and executive functions that may occur in the determination of the level of impairment was thought to contribute to the development of treatment programs. Method: The study group consisted of 60 patients with untreated MDD who were admitted to the psychiatry outpatient clinic at Adana Mental Health and Diseases Hospital and a control group consisting of 30 people who were not diagnosed with depression similar to age and gender. Patients who had previously been treated with a psychiatric diagnosis and who had a history of drug or psychotherapy during the last 6 months were excluded from the study. Beck Depression Inventory (BDI) and Trail Making Test (TMT) were used as measuring instruments. Results: In the study, it was determined that the deterioration in cognitive functions was significantly higher in the untreated MDD patients than in the healthy control group. TMT scores were significantly different between the patient and the control group (p<0.005). A positive and linear relationship between the clinical severity of depression and the level of cognitive impairment was obtained (A+B time; r=0.52, p<0.01). Discussion: In the early period, cognitive impairment should be considered in patients with MDD and treatments aimed at cognitive impairment should be included.
In this study, we aimed to determine the early stage of cognitive impairment in newly diagnosed Major Depressive Disorder (MDD) patients by comparing them with the healthy control group. The cognitive functions of the people diagnosed with depression, especially attention, psychomotor speed and executive functions that may occur in the determination of the level of impairment was thought to contribute to the development of treatment programs. Method: The study group consisted of 60 patients with untreated MDD who were admitted to the psychiatry outpatient clinic at Adana Mental Health and Diseases Hospital and a control group consisting of 30 people who were not diagnosed with depression similar to age and gender. Patients who had previously been treated with a psychiatric diagnosis and who had a history of drug or psychotherapy during the last 6 months were excluded from the study. Beck Depression Inventory (BDI) and Trail Making Test (TMT) were used as measuring instruments. Results: In the study, it was determined that the deterioration in cognitive functions was significantly higher in the untreated MDD patients than in the healthy control group. TMT scores were significantly different between the patient and the control group (p<0.005). A positive and linear relationship between the clinical severity of depression and the level of cognitive impairment was obtained (A+B time; r=0.52, p<0.01). Discussion: In the early period, cognitive impairment should be considered in patients with MDD and treatments aimed at cognitive impairment should be included.
Açıklama
Anahtar Kelimeler
Major depresyon, Erken dönem, Yürütücü işlevler, Dikkat, Psikomotor hız, Major depression, Early period, Executive functions, Attention, Psychomotor speed
Kaynak
Klinik Psikiyatri Dergisi
WoS Q Değeri
N/A
Scopus Q Değeri
Q4
Cilt
22
Sayı
4
Künye
Salık, S., Çakmak, S., & Uğuz, Ş. (2019). Cognitive functions in the early period in non-treated major depression patients. [Tedavi almamış major depresyon hastalarında erken dönemde bilişsel işlevler] Klinik Psikiyatri Dergisi, 22(4), 408-415. doi:10.5505/KPD.2019.55706
